Dr. Lorna Marshall

In clinical practice in the Seattle area since 1987

Residency in Obstetrics & Gynecology at University of California San Diego

Board Certified in Obstetrics & Gynecology

Subspecialty Training in Reproductive Endocrinology & Infertility at University of California San Francisco

Board Certified in Reproductive Endocrinology & Infertility

Clinical Professor in the Department of Obstetrics and Gynecology at University of Washington

Past President and Current Officer of the Pacific Coast Reproductive Society

Top Doctor Honors by Seattle magazine and Seattle Metropolitan magazine

Lorna Marshall, M.D., has been a practicing specialist in Reproductive Endocrinology & Infertility in the Seattle community for over 25 years. Together with Dr. Lee Hickok, she started Pacific NW Fertility in 2005, and has participated in its rapid growth to become the premier fertility clinic it is today. “One of the unique aspects of our center is that each patient gets the personalized care of one physician, while each physician and staff member in the practice feels committed to the success of every patient,” she says. A graduate of the Honors Program in Medical Education at Northwestern University Medical School, Dr. Marshall completed her residency in Obstetrics & Gynecology at the University of California at San Diego and a fellowship in Reproductive Endocrinology at the University of California at San Francisco, where she also served as a faculty member. After moving to Seattle in 1987, she practiced at Virginia Mason Medical Center for 18 years, where she initiated and led the fertility clinic there before opening Pacific NW Fertility. “I have been privileged to participate in many of the advances of in vitro fertilization in my career; I love the perspective this gives me to individualize care for my patients,” says Marshall.

Dr. Marshall is board certified in both Obstetrics & Gynecology and Reproductive Endocrinology & Infertility.

She is a leader in the field of fertility and gynecology locally, regionally, and nationally. She is currently serving as Medical Director of Pacific NW Fertility and as Clinical Professor in Obstetrics & Gynecology at University of Washington Medical School. She is a past President of Seattle Gynecological Society, Pacific Coast Reproductive Society, and the Women’s Council of the American Society of Reproductive Medicine (ASRM). She is on the board of Pacific Coast Ob/Gyn Society, where she is the chair of the Seattle Caucus.

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For many years Dr. Marshall has been involved in ethical issues of reproduction, earning a medical certificate in Health Care Ethics from the University of Washington in 2008. She sat on the ethics committees of the American Society of Reproductive Medicine and the American College of Obstetrics and Gynecology, where she helped write many of the societies’ position papers in reproductive ethics. She was also called on to help create a national consent form for in vitro fertilization. She is committed to helping all aspects of the fertility community. Together with Dr. Julie Lamb, she oversees the fertility preservation program for cancer patients. Recently, she assisted on a RESOLVE project to educate providers on best practices for embryo donation programs.

Dr. Marshall lives in Seattle with her husband and twin daughters. Of her work she says, “It is a pleasure to practice at Pacific NW Fertility, where I am surrounded by so many professionals that are passionate about improving the experience and the outcomes for our patients.”

Board Certification

American Board of Obstetrics & Gynecology, Reproductive Endocrinology

Fellowship

University of California, San Francisco

Residency

Obstetrics & Gynecology at University of California, San Diego

Medical School

Northwestern University Medical School

  • Infertility diagnosis and treatment
  • Donor egg options, including Donor Egg Bank In Vitro Fertilization (IVF)
  • In Vitro Fertilization (IVF)
  • Fertility preservation (Egg and Embryo freezing) in the setting of a cancer diagnosis
  • Elective fertility preservation
  • Hysteroscopic surgery
  • Infertility at an advanced age and/or with diminished ovarian reserve
  • Preimplantation genetic screening (PGS)/Chromosomal screening – Genetic screening of embryos before pregnancy
  • Uterine anomalies
  • Surrogacy
  • Donor sperm

Hospital privileges: Swedish Medical Center

Read more about Dr. Marshall on her Swedish Medical Center physician profile page.

  • Fellow, American College of Obstetrics and Gynecology
  • American Society of Reproductive Medicine
  • Society of Reproductive Endocrinologists
  • King County Medical Society
  • Washington State Medical Association
  • American Medical Association
  • Pacific Coast Reproductive Society
  • Pacific Coast Obstetrical & Gynecological Society
  • Seattle Tacoma Area Reproductive Society
  • Seattle Gynecologic Society (President, 2005-2006)
  • Officer Student Senate - Northwestern University Medical School
  • Alpha Omega Alpha Medical Honor Society - American Medical Women's Association Citation for Academic Excellence
  • NIH Research Training Grant NIH
  • Clinical Associate Physician (CAP) Award
  • Clinical Faculty Teaching Award - University of Washington Department Ob/Gyn
  • Cited as a Top Physician in the Field of Infertility - by the Center for Study of Services
  • Seattle Top Doctor Award, Seattle Metropolitan Magazine - Selected by peers
  • US News Top Doctor Award, US News - Selected by peers

Frequent local, national, international lecture topics: Fertility preservation for cancer patients, age and fertility, ethical issues in reproductive technologies, cross border reproductive care, assisted reproductive technologies, polycystic ovarian syndrome, third party reproduction, menopause and hormone replacement, exercise-associated amenorrhea, endometriosis, operative endoscopy, cancer and hormones. Complete list on request. Some representative examples:

“Cross Border Reproductive Care,” as part of the Ken Ryan Memorial Ethics Symposium, 66th Annual meeting of the American Society of Reproductive Medicine, Denver, October 2010.

“Third Party Reproduction: Issues Physicians Encounter,” at a symposium on Reproduction and the Law, sponsored by the American Association of Law Schools, Vancouver B.C, 2007.

“PCOS-New Horizons,” American College of Physicians Annual Meeting, Seattle, November 2008.

The following documents can be found on  PubMed.gov:

  1. Marshall L. Chapters on "Obstetrics", "Gynecology", and "The Breast" in Lane (ed.),Medical Litigation Guide,Callaghan,1981.
  2. Marshall LA, Andreyko JA, Jaffe RB 1986 Hypothalamic and pituitary control of folliculogenesis and ovulation. In Bringer (Ed.)Induction and Stimulation of ovulation,1986
  3. Andreyko JL, Marshall LA, Dumesic DA, Jaffe RB. Therapeutic uses of gonadotropin releasing hormone analogs. Obstet Gynecol Surv.1987;42:1
  4. Marshall LA, Monroe SE, Jaffe RB. Physiologic and therapeutic aspects of GnRH and its analogs. In Ganong & Martini (Ed.),Frontiers in Neuroendocrinology,1988.
  5. Andreyko JL, Blumenfeld ZB, Marshall LA, Hricak H, Monroe SE, Jaffe RB. Use of an agonistic analog of gonadotropin-releasing hormone (nafarelin) to treat leiomyomata: Assessment by magnetic resonance imaging.Am J Obstet Gynecol1988;158:903
  6. Marshall LA, Martin MC, Leong S, Jaffe RB. Influence of preovulatory estradiol concentrations on LH diurnal secretory patterns: A hypothesis for the timing of the LH surge. Am J Obstet Gynecol1988;159:1558-1563
  7. Marshall LA, Martin MC, Leong S, Jaffe RB.Influence of preovulatory estradiol concentration on diurnal and pulsatile patterns of prolactin secretion. Am J Obstet Gynecol1988;159:1558-63
  8. Jaffe RB, Plosker S, Marshall L, Martin MC. Neuromodulatory regulation of gonadotropin-releasing hormone pulsatile discharge in women.Am J Obstet Gynecol1990;163:1727-31.
  9. Khoury EL, Marshall LA. Luteinization of human granulosa cells in vivo is associated with expression of MHC Class II antigens. 1990;Cell Tissue Res260:217-24
  10. Marshall LA, Fluker MR, Jaffe RB, Monroe SE. Inhibition of follicular development by a potent antagonistic analog of gonadotropin releasing hormone (detirelix).J Clin Endocrinol Metab1991;72:927-933
  11. Fluker MR, Marshall LA, Jaffe RB, Monroe SE. Variable ovarian response to gonadotropin-releasing hormone antagonist-induced gonadotropin deprivation during different phases of the menstrual cycle. J Clin Endocrinol Metab1991;72:912-919
  12. Andreyko JL, Monroe SE, Marshall LA, Fluker MR, Nerenberg CA, Jaffe RB. Concordant suppression of serum immunoreactive luteinizing hormone (LH), follicle-stimulating hormone, alpha subunit, bioactive LH, and testosterone in postmenopausal women by a potent gonadotropin releasing hormone antagonist (detirelix). J Clin Endocrinol Metab1992;74:399-405
  13. Fluker MR, Marshall LA, Jaffe RB, Monroe. Contrasting effects of a GnRH agonist and antagonist upon the secretion of intact gonadotropins and free alpha subunit. Fertil Steril1994;61:573-575
  14. Marshall , Fleming K. The role of education in the management of the menopause.Virginia Mason Clinic Bulletin1992;46:15-20
  15. Marshall LA. Clinical evaluation of amenorrhea in active and athletic women. In Agostini RA (ed)Clinics in Sports Medicine,W.B.Saunders, April, 1994
  16. Marshall LA. Clinical evaluation of amenorrhea. In Agostini RA (ed)Medical and Orthopedic Issues in Active and Athletic Women,Hanley & Belfus, 1994
  17. McClure RD, Marshall LA. Endocrinologic sexual dysfunction. in Singer, Warner (ed)Sexual Dysfunction: A Neuro-Medical Approach,1994.
  18. Marshall LA. Caring for the infertile female patient and her partner.Internal Med1994;15:4:18-38.
  19. Marshall L. The effect of weight, stress, and exercise on fertility. Resolve National Newsletter, Winter, 1994
  20. Marshall LA, Cain J. Ethical issues. In: Lemcke DP, Pattison J, Marshall LA, Cowley DS (eds)Primary Care of Women. Appleton & Lange, 1995, pp47-9.
  21. Marshall LA. Hirsutism. In: Lemcke DP, Pattison J., Marshall LA, Cowley DS (eds).Primary Care of Women.Appleton & Lange, 1995, pp144-48.
  22. Lemcke DP, Marshall LA, Pattison J. Menopause & hormone replacement therapy. In: Lemcke DP, Pattison J, Marshall LA, Cowley DS (eds) Primary Care of Women. Appleton & Lange, 1995, pp161-72.
  23. Marshall LA. Infertility. In: Lemcke DP, Pattison J, Marshall LA, Cowley DS (eds)Primary Care of Women.Appleton & Lange, 1995, pp499-505
  24. Marshall LA, Cain DF, Dmowski WP, Chestnut C III. Urinary N-telopeptides to monitor bone resorption on gonadotropin-releasing hormone agonist therapy.Obstet Gynecol.1996;87:350-354.
  25. Marshall LA. Intergenerational gamete donation: Ethical & societal implications.Am J Obstet Gynecol.1998;178:1171-6
  26. Marshall LA. Facial Hair on Women: Diagnosing and treating a pathological twist on a common problem. Medscape. Women's Health.February, 1997.
  27. Angle M, Tom R, Marshall L, Letterie GS. Correlation between elevated levels of single stranded DNA in inseminating sperm populations and failure to conceive during intracytoplasmic sperm injection. In:In Vitro Fertilization and Assisted Reproduction, proceedings of the 10th World Congress in IVF. Eds, Vigamel and PCK Leung. Monduzzi Editoire, Bologna, Italy, 1997 pp575-579
  28. Letterie GS, Angle M, Marshall L. Beneficial effect of assisted hatching for poor prognosis alone and in conjunction with intracytoplasmic sperm injection for both poor prognosis and severe male factor candidates. In:In Vitro Fertilization and Assisted Reproduction, Proceedings of the 10th World congress in IVF. Eds, Vigamel and PCK Leung. Monduzzi Editoire, Bologna, Italy, 1997 pp695-699
  29. Marshall LA. Amenorrhea in the female athlete. In:Encyclopedia of Sports Medicine: Woman in Sport.Ed, Drinkwater BL. Blackwell Science Ltd, Oxford, England, 1999
  30. Marshall LA. Female infertility. In: Greene HL, Johnston WP, Lemcke D (eds).Decision-Making in Medicine – An Algorithmic Approach.St. Louis, Mosby, 1998, pp. 498-501.
  31. Marshall LA. Review of Textbook of Reproductive Medicine (and study guide). Carr, Blackwell, eds.JAMA1999; 282:695.
  32. Marshall LA, Emrich JA, Hjelm M, Shandell AP, Letterie GS. What motivates paid egg donors? In: Jansen R and Mortimer D (eds).Toward Reproductive Certainty: Fertility and Genetics Beyond.London, Parthenon Publishing Group, Ltd, 1999.
  33. Letterie GS, Marshall LA, Angle MA. A new coaxial catheter system with an echodense tip for ultrasound-guided embryo transfer.Fertil Steril1999;72:266.
  34. Marshall LA. Amenorrhea. In:International Encyclopedia of Women and Sport.MacMillan, New York, 2001.
  35. Marshall LA. Menstrual cycle. In:International Encyclopedia of Women and Sport.MacMillan, New York, 2001.
  36. Letterie GS, Marshall L. Evaluation of real-time imaging using a laparoscopic ultrasound probe during operative endoscopic procedures. Ultrasound Obstet Gynecol2000;15:1-5.
  37. Marshall LA. Infertility. PIER Module (on-line). American College of Physicians, 2002.
  38. Marshall LA. Ethical issues (infertility). In:Precis: Reproductive Endocrinology. American College of Obstetrics and Gynecology, Washington DC, 2002.
  39. Marshall LA. Ethical and legal issues in the use of related donors for therapeutic insemination.Urol Clin N Am2002;29:855-861.
  40. Letterie GS, Marshall LA. Intrauterine reflux of media during cervical irrigation at embryo transfer. Fertil Steril2003;
  41. Marshall LA. Ethical issues. In Lemcke D, Pattison J, Marshall LA, Cowley DS (eds).Current Diagnosis and Treatment of Women. McGraw-Hill,2004, pp 16-20.
  42. Marshall LA. Polycystic Ovary Syndrome. In Lemcke D, Pattison J, Marshall LA, Cowley DS (eds).Current Diagnosis and Treatment of Women. McGraw-Hill,2004, pp 165-173.
  43. Marshall LA. Infertility. In Lemcke D, Pattison J, Marshall LA, Cowley DS (eds).Current Diagnosis and Treatment of Women. McGraw-Hill,2004, pp 563-571
  44. Letterie G, Marshall L, Angle M. The relationship of clinical reponse, oocyte number, and success in oocyte donor cycles.J Assist Reprod Genet2005;22:115-7.
  45. Marshall L. Fertility policies in the age of Octomom.American Forum, March 2009 (republished in multiple newspapers and on-line sites).
  46. Craig LB, Hullender Rubin LE, Peck JD, Anderson M, Marshall LA, Soules MR. Acupuncture performed before and after embryo transfer: A randomized controlled trial.J Reproductive Medicine2014;In Press.
  47. Lamb J, Khabani A, Khabani C, Hickok L, Shahine LS, Marshall LA. Blastocysts developed from vitrified banked donor oocytes: An affordable, efficient and successful option for patients needing egg donation. Submitted for publication.
  1. Lemcke D, Pattison J, Marshall LA, Cowley DS (eds). Primary Care of Women. Appleton & Lange, 1995
  2. Lemcke D, Pattison J, Marshall LA, Cowley DS (eds).Current Diagnosis and Treatment of Women. McGraw-Hill, 2004.
  1. Marshall L, Licko V, Martin M. 1985 Estrogen increased basal and pulsatile prolactin without altering sensitivity to dopamine. Abstract #159. The Endocrine Society.
  2. Marshall L, Leong S, Martin M 1986 Effect of estradiol on LH and prolactin circadian pulsatile rhythms. Abstract #216, Society for Gynecologic Investigation.
  3. Andreyko J, Blumenfeld Z, Marshall L, Hricack H, Cann C, Monroe S 1986 Treatment of uterine leiomyomata with a GnRH agonist. Abstract #127, Society for Gynecologic Investigation.
  4. Marshall LA, Martin MC, Jaffe RB 1986 Evidence against a common release mechanism for PRL and LH in women. Abstract, First International Congress of Neuroendocrinology.
  5. Dandekar P, Martin M, Andreyko J, Marshall L, Taylor R, Dumesic D, Monroe S, Glass R 1986 Polyovular follicles in IVF patients. Abstract #149, The American Fertility Society.
  6. Martin M, Andreyko J, Marshall L, Dumesic D, Taylor R, Glass R 1986 The role of washed intrauterine insemination in treatment of fertility. Abstract #321, The American Fertility Society.
  7. Andreyko JL, Marshall L, Hoffman P, Jaffe R, Monroe S 1987 Gonadotropins regulate testosterone secretion in postmenopausal women. Abstract #287, Society for Gynecologic Investigation.
  8. Fluker MR, Marshall LA, Jaffe RB, Monroe SE 1988 Contrasting biological effects and therapeutic potential agonistic and antagonistic analogs of gonadotropin releasing hormone. Abstract #218, Society for Gynecologic Investigation.
  9. Jaffe RB, Marshall LA, Martin MC 1988 Prolactin and gonadotropin regulation in euprolactinemic and hyperprolactinemic states. Sandoz International Symposium on Prolactin in Human Reproduction, Kyoto, Japan.
  10. Khoury EL, Marshall LA 1988 Luteinization of granulosa cells in human ovaries is associated with expression of MHC Class II antigens. Abstract #685, The Endocrine Society.
  11. Fluker MR, Marshall LA, Monroe SE, Jaffe RB 1988 Maturational changes in the dominant follicle as revealed by a potent GnRH antagonist Abstract #879, The Endocrine Society.
  12. Fluker MR, Marshall LA, Jaffe RB, Monroe SE 1989 Contrasting effects of a GnRH agonist and antagonist upon intact gonadotropin and free alpha subunit secretion. Abstract #937, The Endocrine Society
  13. McClure RD, Angle MA, Letterie GS, Marshall LA. 1995 New hope for severe male factor infertility: intracytoplasmic sperm injection (ICSI) Western Section American Urological Association
  14. Shary J, Bell NH, Marshall L, Sanfilippo J, Ramos J, Johnston CC, Mallinak N, Cain D, Flesslan K. 1995 Comparison of three types of urine collections for measurement of urinary N-telopeptide of type I collagen. Am Soc Bone Mineral Research
  15. Angle M, Tom R, Morse K, Marshall LA, Letterie GS. 1997 Correlation between elevated levels of single stranded DNA in inseminating sperm populations & failure to conceive during ICSI Abstract #PP-01-004, 10th World Congress on In Vitro Fertilization
  16. Letterie GS, Angle M, Marshall L. 1997 Beneficial effect of assisted hatching for poor prognosis alone & in conjunction with intracytoplasmic sperm injection for both poor prognosis and severe male factor candidates. Abstract #PP-07-104, 10th World Congress on In Vitro Fertilization
  17. Marshall LA. 1997 Transgenerational gamete donation: ethical & societal implications. Pacific Coast Obstetrical & Gynecological Society
  18. Letterie GS, Marshall L, Angle M. A "coasting" period to prevent ovarian hyperstimulation syndrome (OHSS) in at risk hyperstimulated cycles for in vitro fertilization (IVF). 53rd Annual Meeting of the American Society for Reproductive Medicine, October 1997
  19. Letterie GS, Marshall L, Angle M. Ovarian response versus age as a predictor of success in in vitro fertilization (IVF). 53rd Annual Meeting of the American Society for Reproductive Medicine, October 1997
  20. Letterie GS, Marshall L, Angle M. Gestational sac discrepancy as a predictor of outcome in twin pregnancies after in vitro fertilization (IVF). 53rd Annual Meeting of The American Society of Reproductive Medicine, October 1997
  21. Letterie GS, Marshall LA, Angle MA, McClure D. Relationship of serum estradiol concentrations to multiple pregnancies after in vitro fertilization. 54thAnnual Meeting of American Society of Reproductive Medicine, October 1998.
  22. Letterie GS, Marshall LA. Real-time laparoscopic ultrasound imaging during complex endoscopic operative procedures. 54thAnnual Meeting of American Society of Reproductive Medicine, October 1998.
  23. Letterie GS, Marshall LA, Angle MA. A new coaxial catheter system with an echodense tip for ultrasound-guided embryo transfer. 54thAnnual Meeting of American Society of Reproductive Medicine, October 1998.
  24. Marshall LA, Letterie GS. Does sonohysterography accurately predict intrauterine pathology? Pacific Coast Reproductive Society, April 1999.
  25. Marshall LA, Emrich JA, Hjelm M, Shandell AP, Letterie GS. What motivates paid egg donors in this era of commercialism? World Congress IVF, Sydney, May 1999.
  26. Marshall LA, Letterie GS, Angle MA. Does blastocyst culture and transfer decrease the efficiency of ovum donation? Pacific Coast Reproductive Society, April 2000.
  27. Letterie GS, Marshall LA, Angle MA. Selection criteria for identifying embryos with a high probability of progressing to blastocyst formation, pregnancy, and implantation. Pacific Coast Reproductive Society, April 2000.
  28. Letterie GS, Marshall LA, Angle MA. Impact of intrauterine reflux of media during cervical irrigation at embryo transfer. 57thAnnual Meeting of American Society of Reproductive Medicine, October 2001.
  29. Letterie GS, Marshall LA, Angle MA. What is the lower threshold of clinical response for donor cycle cancellation? Relationship of clinical response, oocyte number, and success in donor cycles. 59thAnnual Meeting of American Society of Reproductive Medicine, October 2003.
  30. Angle MJ, Aliabadi J, Patrick C, Congdon J, Marshall L. Simultaneous culture of embryos in two separate sequential media systems improves pregnancy outcomes. 61stAnnual Meeting of American Society of Reproductive Medicine, October 2005.
  31. Khabani A, Khabani C, Hickok, LR, Woodford DE, Marshall LA. A novel technique to perform ICSI in a case of defective zona pellucida. Pacific Coast Reproductive Society, April 2007
  32. Hickok LR, Marshall LA, Woodford DE, Khabani CL, Khabani A. Falsely elevated serum estradiol levels due to heterophilic antibodies in three women undergoing in vitro fertilization. Pacific Coast Reproductive Society, April 2007.
  33. Craig L, Criniti A. Hansen K, Marshall L, M Soules M. Acupuncture lowers pregnancy rates when performed before and after embryo transfer. 63rdAnnual Meeting of American Society of Reproductive Medicine, October 2007. Prize paper candidate.
  34. Lamb J, Khabani A, Khabani C, Frickleton S, Shahine L, Marshall L, Hickok L. Donor oocyte vitrification provides an efficient, affordable, and successful option for patients needing egg donation. Pacific Coast Reproductive Society, April 2012.

We had an excellent experience!  Very quick response to questions/emails.  Very professional.  The clinic is like a well oiled machine.  Everybody is very friendly and went out of their way to make sure we had a great experience.

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